Make a donation. (blue colour), Corynebacterium spp. Apocrine secretion can be triggered by emotions (stress and anxiety), rubbing of apocrine-heavy areas (friction from clothes) and hot showers and baths, so doing what you can to reduce these triggers practicing mindfulness, wearing breathable clothing, taking lukewarm showers can be a solid first step. These colors are due to a pigment produced in the sweat glands called lipofuscin. Lett Appl Microbiol 2014; 58: 2530. Pediatrics 2005; 115: e239241. Indian J Dermatol 2016; 61: 454457. International Hyperhidrosis Societyhas received theGuideStar Exchange Seala leading symbol of transparency and accountability provided by GuideStar, the premier source of nonprofit information. Galadari H, et al. "Finding and stopping the specific cause is paramount.". Lipofuscin can be produced in the apocrine glands, and when it occurs in high enough . What is Chromhidrosis? Causes and Treatments - Duradry Best food forward: Are algae the future of sustainable nutrition? It occurs most often in babies and small children. Eccrine chromhidrosis resembling clinical features of pompholyx with bile-like greenish pigmentation on the right palm and soles. JAMA 1977; 238: 1628. If you are experiencing serious medical symptoms, please see the Epidermolysis bullosa, a connective tissue disorder that causes fragile skin that blisters and tears easily. All bacteriological swabs of female patient (neck, upper arm, axilla, hand, and foot) had heavy growth of 2 strains of Bacillus cereus. The phenomenon might be thanks to chromhidrosis, a rare skin condition marked by the production of colored sweat (think: blue, green, yellow, red, brown or black). It could be removed with soap and water; however, it was more easily removed with alcohol wipes (Fig. Wu JM, Mamelak AJ, Nussbaum R, McElgunn PS. Clinical photographs. Uzoma M, Singh G, Kohen L. Green palmoplantar vesicular eruption in a patient with hyperbilirubinemia. Dermatol Monatschr 1972; 158: 18. The patient performed 15 min of indoor cycling and 15 min of treadmill running. Sweat When You Eat? People sweat due to heat, stress, and a range of other causes. Valeru SP, Rompikuntal PK, Ishikawa T, Vaitkevicius K, Sjling A, Dolganoy N, et al. On the contrary, the patient reported daily attacks of cholinergic and dermographic urticaria, and hypohidrosis even after strenuous exercise and emotional stimuli. Multiple bacteriological and mycological swabs were taken from all 3 family members. Infect Immun 2009; 77: 935942. The authors have no conflicts of interest to declare. Lan L, Cheng A, Dunman PM, Missiakas D, He C. Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus. Stomach Flu: Is It Contagious, and How Long Does It Last? - Healthline II. Apocrine glands open into the hair follicle, leading to the surface of the skin. Dr. Hines has extensive experience in both common and rare conditions. Christoffer Aam Ingvaldsen1,2, Truls Michael Leegaard2,3, Gunnhild Kravdal4 and Cato Mrk5. information is beneficial, we may combine your email and website usage information with Triwongwaranat D, Kasemsarn P, Boonchai W. Green pigmentation on the palms and soles. Retrospectively, her husband also recognized slight blue discolouration located on his right pectoral and deltoid region. Chromhidrosis is a rare idiopathic disorder characterized by colored secretions most typically from the malar cheeks, axilla, or areolar regions. Geelhoed-Duijvestijn PHLM. We report here a case of blue infectious pseudochromhidrosis caused by pigment-producing Bacillus cereus and the results of a literature review. information and will only use or disclose that information as set forth in our notice of 4th edn. No wheals were induced during exercise. Your body has two types of sweat glands, apocrine and eccrine. We hypothesized that the female patient was the source. And the sweating usually happens on both sides of the body. 3. In this article, learn more about what chromhidrosis is, what causes it, and what treatments are available. Can diet help improve depression symptoms? July 30, 2022. J Am Acad Dermatol 2005; 53: 869871. Magyarosy A, Ho JZ, Rapoport H, Dawson S, Hancock J, Keasling JD. E-mail: c.a.ingvaldsen@medisin.uio.no. Chromhidrosis - UpToDate The lack of discolouration in the newborn may reflect the absence of the specific requisite milieu for this pigment-producing Bacillus spp. Either way, because the condition is chronic, treatment will need to be maintained for continuous results. Chromhidrosis means discoloured sweat. While it isn't life-threatening, chromhidrosis often causes emotional distress. Depending on the cause of your child's pink eye, signs and symptoms usually improve within a few days to two weeks. JAAD Case Rep 2017; 3: 273275. Chromhidrosis is a chronic condition that causes a person to have colorful sweat. Appl Environ Microbiol 2009; 75: 493503. Schmaler-Ripcke J, Sugareva V, Gebhardt P, Winkler R, Kniemeyer O, Heinekamp T, et al. Banerjee D, Chatterjee S, Banerjee UC, Guha AK, Ray L. Green pigment from Bacillus cereus M(1)(16) (MTCC 5521): production parameters and antibacterial activity. Accessed June 16, 2022. Hyperhidrosis treatment usually helps. However, studies do not mention the exact pigments causing blue and brown/black discolouration: B. cereus has been shown to produce both a green (84, 88) and a red pigment (85). Kaya TI, Delialioglu N, Yazici AC, Tursen U, Ikizoglu G. Medical pearl: blue underpants sign a diagnostic clue for Pseudomonas aeruginosa intertrigo of the groin. Publish modules to the "offcanvas" position. Treatment options for the other two types of chromhidrosis are more promising, though: "Eccrine and pseudochromhidrosis may completely resolve once the cause is avoided or treated," Dr. Friedmann says. What the Smell of Your Pimples Can Tell You About Your Skin Health, This Is Why Your Armpits Smell Even With Deodorant. Additionally, stress or physical activity may trigger colored sweat in people with chromhidrosis. Interestingly, our patients unspecified hypohidrotic condition could, in fact, have been intensified by the use of promethazine: Zahejsky & Rovensky reported a significant reduction in palmar sweating after administration of promethazine in their clinical study (101). Is Chromhidrosis Behind Your Blue Toilet Seat? | livestrong reported a novel Corynebacterium spp. (brown/black colour), Serratia marcescens (red/pink colour), and Pseudomonas aeruginosa (blue-green colour). Infections in those with higher risk may last longer. Posted at 18:52h in houses for rent in sanger, ca century 21 by sabinas mountain boerne, tx. However, patients with the condition report stress and embarrassment, as well as anxiety and depression related to their symptoms. The treatment options currently available focus on reducing symptoms as much as possible, but there's no cure. 2017; doi: org/10.1016/j.disamonth.2017.03.003. Secondary hyperhidrosis is caused by an underlying medical condition or by taking certain medications, such as pain relievers, antidepressants, and some diabetes and hormonal medications. Dermatol Surg 2005; 31: 963965. The coloration may be barely noticeable and restricted to a few locations or more. Trends Microbiol 2009; 17: 406413. Review of reported cases of chromhidrosis. Symptoms usually appear within one to two days of exposure. Jaiswal AK, Ravikiran SP, Roy PK. Chromhidrosis - PubMed The best treatment depends on the type of chromhidrosis: Treatment for this type of chromhidrosis either aims to reduce the amount of sweat or to induce the sweat and empty the glands. J Bacteriol 1953; 65: 509510. Apocrine chromhidrosis affects the areas of the body that contain apocrine sweat glands. The blue toilet seat phenomenon is still somewhat of a mystery, but signs point to a condition called chromhidrosis. The B. cereus strains are referred to as B. cereus in the following text. Skin Diseases: 15 Uncommon Skin Conditions - MedicineNet This content does not have an English version. Mayo Clinic; 2021. Arch Microbiol 2018; 200: 989999. No skin discolouration was seen on their child. Moreover, there is no clear consensus in terms of disease triggers, causative microorganisms, and factors contributing to the clinical presentation of coloured sweat. Hyperhidrosis and anhidrosis. Koley S, Mandal RK. This process might involve your doctor testing skin scrapings, secretion smears and extraction samples from clothing. Lipofuscins are yellow-brown pigment granules made of fat-like residues. Sweating causes emotional distress or social withdrawal, You suddenly begin to sweat more than usual, You experience night sweats for no apparent reason. Chromhidrosis is harmless, but it can cause embarrassment or distress that may lead to depression or anxiety. They're fatty deposits of cholesterol caused by very high levels of triglycerides, a type of fat in your blood. Molecular evidence of person-to-person transmission of a pigmented strain of Corynebacterium striatum in intensive careunits. J Dermatol 2006; 33: 230231. This form of colored sweat is seen when normal perspiration at the skin surface interacts with other compounds, such as dyes (from a new pair of jeans, perhaps), chemicals (a la sunless tanning sprays) or chromogenic bacteria on the skin (bacteria that produce pigments), Dr. Friedmann says. You may opt-out of email communications at any time by clicking on Pistone G, Bellomo L, Alaimo R, Bongiorno MR. Pseudochromhidrosis: the role of dermoscopy in diagnosis. Bromhidrosis: Causes, Treatment, and More - Healthline They may then run or request tests to rule out other causes of the discoloration. Griffith JR. Isolated areolar apocrine chromhidrosis. PloS One 2018; 13: e0194346. You may sweat so much that it soaks through your clothes or drips off your hands. Hand-foot-and-mouth disease - Symptoms and causes - Mayo Clinic Key words: chromhidrosis; pseudochromhidrosis; infectious pseudochromhidrosis; coloured sweat; pigment. Blalock TW, Crowson AN, Danford B. We avoid using tertiary references. Tuberculosis - Symptoms and causes - Mayo Clinic It is more common than chromhidrosis. Other causes of bronchitis aren't contagious. Chromhidrosis is a rare condition with a characteristic presentation of the secretion of colored sweat and was first reported by Yonge in 1709. 2). "All apocrine fluid contains yellow-brown granules called lipofuscin," Dr. Friedmann says. Experts: GARD is not currently aware of a specialist directory for this condition. However, stress or embarrassment about the coloration can lead to depression and anxiety. Coughing up blood or mucus. Chromhidrosis is a rare condition characterized by the secretion of colored sweat. Eccrine glands secrete a clear, odorless fluid that. Sweating a different color -- like yellow, blue, green, or black -- is a different condition called chromhidrosis. Production of pyomelanin, a second type of melanin, via the tyrosine degradation pathway in Aspergillus fumigatus. The blue colour was present continuously, but was more obvious after physical activity. Acral green pigmentation (eccrine chromhidrosis). AMA Arch Derm Syphilol 1954; 69: 449471. Oliveira A, Oliveira LC, Aburjaile F, Benevides L, Tiwari S, Jamal SB, et al. Chromhidrosis: Definition, causes, and treatment - Medical News Today causes the sweat glands to secrete colored sweat. pH measurements of sweat were considered normal (mean/minmax: 5.6/5.16.5). It often begins with antiperspirants. Usually, chromhidrosis affects the apocrine glands, mainly on the face and underarms. If a person notices any coloration, they should consult a doctor. Tempark T, Wittayakornrerk S, Jirasukprasert L, Chatproedprai S, Wananukul S. Pseudochromhidrosis: report and review of literature. Although you typically feel better after a day or two, you're contagious for a few days after you recover. In some cases, ingesting of certain substances causes discoloration of sweat. Williamson et al. Chromhidrosis causes the sweat glands to secrete colored sweat. Chromhidrosis | DermNet The latter approach can stop the sweat from happening for up to 3 days at a time. Facial and axillary apocrine chromhidrosis. Clinicals pearls in dermatology 2017. Liu GY, Nizet V. Color me bad: microbial pigments as virulence factors. Several factors can increase sweating in the, Butt sweat can happen in various situations, such as while exercising. Both adults were treated with oral erythromycin, 250 mg 3 times a day, and topical clindamycin 2 times a day for 10 days. Gawkrodger DJ, et al. You can spread the common cold from a few days before your symptoms appear until all of the symptoms are gone. The bleeding usually stops on its own, and it's not serious, although it can make . Australas J Dermatol 2016; 57: e2325. This site complies with the HONcode standard for trustworthy health information: verify here. With pseudochromhidrosis, sweat takes on an unusual color after secretion from the sweat gland as it comes in contact with dyes, chemicals, or chromogenic bacteria on the skin (bacteria that produce pigments.). Corynebacterium spp. (9094). (b) Diffuse blue discolouration with an ashen hue on dorsal side of the foot. Can your sweat be different colors? | HowStuffWorks Dermoscopy of the discoloured areas revealed diffuse superficial pigmentation and an unmodified skin pattern (as postulated by Pistone et al. Infectious Pseudochromhidrosis: A Case Report and Literature Review, Copyright Acta Dermato-Venereologica. Shelley WB, Hurley HJ, Jr. International Hyperhidrosis Society. They're the glands that secrete a milky, odorless substance when you're stressed, and when that combines with bacteria on your skin, it causes body odor, according to the Mayo Clinic. All rights reserved. Clin Dermatol 2015; 33: 483491. Corynebacterium species brown/black IPCH (44, 49, 50): Corynebacterium is a genus of Gram-positive and (mostly) aerobic rods that is widely distributed in nature. J Clin Diagn Res 2013; 7: 243246. Eccrine glands are distributed with varying density over almost the entire integument and excrete large amounts of sweat, containing mostly water and electrolytes (1, 3). How long is someone contagious after a viral infection? - NHS People with chromhidrosis may have more lipofuscin, or lipofuscin that is more oxidized, than others. They can rule out more serious causes and recommend any necessary treatment. Chromhidrosis Necrobiosis lipoidica Contacting a doctor Summary The skin is the largest organ of the human body. Several techniques can, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Bull Soc Fr Dermatol Syphiligr 1965; 72: 444447. Bernard K. The genus corynebacterium and other medically relevant coryneform-like bacteria. Pediatr Dermatol 2018; 35: 448452. Bromhidrosis is foul-smelling body odor related to your sweat. Burkovski A. Corynebacteria: genomics and molecular biology. Role of melanin pigment in expression of Vibrio cholerae virulence factors. Learn more here. reported blue skin discolouration due to Bacillus spp. Real Talk: Why Does Sweat Smell So Bad After Certain Workouts? Another important observation in the current case report was that B. cereus colonized and produced pigments in both adults, but not in the newborn. Derivatives of the skin. Bacillus cereus: 2 isolates; one with a blue tint and one without. These colors are due to a pigment produced in the sweat glands called lipofuscin. Eccrine chromhidrosis. The blue discolouration appeared 23 weeks after his wifes. Indian J Dermatol 2017; 62: 675. ", Always Sweating in Your Sleep? The type of hyperhidrosis that usually affects the hands, feet, underarms or face causes at least one episode a week when you're awake. Chromhidrosis. To date, none of the previous studies have specifically reported a blue pigmentation as a result of colonization with B. cereus. Hyperhidrosis treatment usually helps. This condition can further subdivide into apocrine chromhidrosis and eccrine chromhidrosis, and the treatment depends on type and cause. Arch Dermatol 2005; 141: 795796. "Because of its wide range of underlying causes, eccrine chromhidrosis can happen at any age," Dr. Friedmann says. G20 with specific anticancer activity. Lack of interest in activities you once enjoyed. There is a problem with They're fatty deposits of cholesterol caused. Mycoses 2006; 49: 388392. Yamada-Ankei T, Iwasaki H, Mori T. Production of copper coproporphyrin III by Bacillus cereus. Here's what experts have managed to suss out about this puzzling skin condition so far: Apocrine, eccrine and pseudochromhidrosis each show up a bit differently and have their own underlying causes, Daniel Friedmann, MD, board-certified dermatologist at Westlake Dermatology in Austin, Texas, tells LIVESTRONG.com. Chromhidrosis is a harmless skin condition, but because colored sweat can be a symptom of something more serious, it's important to check in with your doctor or dermatologist for an official diagnosis. Greenberg L. Serratia marcescens in human affairs. What is the latest research on the form of cancer Jimmy Carter has? Wang A, Wysong A, Nord KM, Egbert BM, Kosek J. Chromhidrosis: a rare diagnosis requiring clinicopathologic correlation. Drewnowska JM, Zambrzycka M, Kalska-Szostko B, Fiedoruk K, Swiecicka I. Melanin-like pigment synthesis by soil bacillus weihenstephanensis isolates from northeastern Poland. Here's What Your Body's Trying to Tell You. also described a single strain of C. striatum that produced a soluble, brown pigment (96). Marshall JH, Wilmoth GJ. Manual expression of the apocrine glands (where you carefully squeeze the glands to empty them, similar to how you'd pop a zit) can also offer relief, but the results only last up to a few days. Chromhidrosis can occur at nearly any age, but it usually becomes noticeable after puberty, when the apocrine glands begin secreting fluid.The International Hyperhidrosis Society (IHS) note that information about this condition is scarce because it is so rare. The virus can remain in your stool for up to two weeks or more after recovery. Polat M, Dikilitas M, Gozubuyukogullari A, Alli N. Apocrine chromhidrosis. Mayo Clinic is a not-for-profit organization. The goal of treatment for chromhidrosis is to reduce symptoms in order to also reduce any related psychosocial impacts or stigma. Fig. Nair PA, Kota RK, Surti NK, Diwan NG, Gandhi SS. privacy practices. For excessive sweating, a range of treatments and strategies can help. She had started daily 25 mg promethazine due to pruritus 6 months earlier. IPCH following administration of an antihistamine. Coloured sweat in two brothers: first report of familial chromhidrosis. Those substances might include water-soluble dyes, heavy metals (like copper), excess food coloring or flavoring, as well as certain medications (rifampin, an antibiotic; quinines, an antimalarial; and levodopa, a dopamine precursor used to manage Parkinson's). I. Purification and identification of copper coproporphyrin III. Whole genome characterization of Bacillus cereus associated with specific disease manifestations. J Appl Microbiol 2017; 123: 12281236. A case of generalized red sweating. It can run in families. Chromhidrosis is a disorder of the sweat glandsthat manifests with colored sweat on the face, in the underarms, or on the areola of the breasts (the darker circle of skin around the nipples). de Carolis P, Magnifico F, Pierangeli G, Rinaldi R, Galeotti M, Cevoli S, et al. Ami T. Allscripts EPSi. The colour of the sweat depends on the dye, drug, or chemical involved, with red, blue, orange, brown, yellow, green, black, and white sweat reported. Sweating is an important bodily function that keeps you cool during hot weather and tough workouts. Chromhidrosis is quite rare with limited information about the percentage of people potentially affected. Haddix PL, Shanks RMQ. Blue Toilet Seat? Why Your Toilet Seat Is Turning Blue True chromhidrosis is a rare condition characterized by the secretion of colored sweat from apocrine or eccrine sweat glands. The same authors also described resolution of both the blue skin discolouration and the Bacillus spp. American Academy of Dermatology Association. From a medical perspective, the pathogenic species C. diphtheriae (diphtheria), C. ulcerans (diphtheria-like infections), C. tenuis (trichomycosis axillaris), C. minutissimum (erythrasma), and C. striatum (endocarditis) might be of greatest interest. Saff DM, Owens R, Kahn TA. Eccrine chromhidrosis is generalized discolouration that occurs secondary to ingestion of water-soluble drugs (2, 27, 28), dyes (2931), or due to breakdown products from eccrine glands (2, 3235). Clin Microbiol Rev 2010; 23: 382398. If a person with chromhidrosis experiences any symptoms of emotional or psychological distress, they should let a healthcare provider know. J Bacteriol 1981; 147: 900913. Microorganisms may produce pigments to increase the likelihood of survival. In other circumstances, health issues such as infection and liver problems may cause sweat to change color. Case reports of infectious pseudochromhidrosis and causative microorganisms. Certain situations stimulate the apocrine glands and make this discoloration more likely to occur: In people with eccrine chromhidrosis, the discoloration usually happens because the person has ingested: Pseudochromhidrosis is more common, and it occurs when the skin comes into contact with: The IHS also point to other health issues that can cause sweat to change color: It is a good idea to see a doctor about colored sweat. One of the B. cereus strains found produced blue pigments on blood agar, but the other did not (Fig. Balasubramanian S, Amperayani S, Dhanalakshmi K, Kumar R. Chromhidrosis colored sweat in a toddler. face, axillae, anogenital area, and breast areolae) that . Afra S, Makhdoumi A, Matin MM, Feizy J. Stomach flu: How long am I contagious? - Mayo Clinic Chang T, Rosch JW, Gu Z, Hakim H, Hewitt C, Gaur A, et al. 3). PCRs for dermatophytes were negative. Wolters Kluwer; 2019. The childs swabs grew no microorganisms other than normal microflora. The literature review revealed a repeated theme of micro-organisms producing pigments. Seek immediate medical attention if you have heavy sweating with dizziness, pain in the chest, throat, jaw, arms, shoulders or throat, or cold skin and a rapid pulse. Her past medical history was insignificant and she had not been diagnosed with any underlying dermatoses. It may be associated with hyperhidrosis. Pseudomonas aeruginosa blue-green IPCH (36, 48, 62): P. aeruginosa is a Gram-negative, aerobic coccobacillus, which is widespread in nature (63). Tracking your daily activities for two to three weeks such as what you've eaten and any chemicals you've come into contact with leading up to your doctor's appointment can be helpful in determining your triggers and what the potential culprits might be. That means the norovirus infection can easily spread to others. Kitamura S, Yanagi T, Imafuku K, Hata H, Shimizu H. Lipofuscin deposition causes the pigmentation of apocrine hidrocystoma. Some people may experience a warm, tingly sensation before the appearance of colored sweat. Green staining of clothing: a signal for pseudomonal infection. Clin Interv Aging 2015; 10: 265267. Serratia marcescens red/pink IPCH (4547): S. marcescens is a Gram-negative, facultatively anaerobic, and saprophytic bacteria belonging to the Enterobacteriaceae family (60, 61). Eccrine chromhidrosis is the production of coloured sweat from the eccrine sweat glands. Appl Environ Microbiol 2002; 68: 40954101. Others have noted thatBotox injectionscan treat chromhidrosis. Dr. Hines has extensive experience in both common and rare conditions. Palmar and digital black pseudochromhidrosis: a case report. The isolates were then subject to matrix-assisted laser desorption ionisation time of flight mass spectrometry (MALDI-TOF MS, Bruker Daltonik GmbH, Bremen, Germany) and 16S rRNA gene sequencing with primers based on MicroSEC 500 16S rDNA bacterial sequencing kit (Life Technologies, Paisley, UK). In apocrine chromhidrosis, apocrine glands release colored sweat affecting mostly the face, ears, scalp, and trunk. PloS One 2015; 10: e0125428. Apocrine chromhidrosis must be distinguished from pseudochromhidrosis and eccrine chromhidrosis. Despite determining survival, pathogenicity, and virulence among microorganisms, we hypothesize that most pigments are mainly produced only under favourable conditions (of pH, temperature, hydration levels, metabolism rate, oxygen tension, growth substrates, etc.). This is a narrative review. Odanaka K, Iwatsuki M, Satho T, Watanabe M. Identification and characterization of a brilliant yellow pigment produced by Bordetella pertussis. Pseudochromhidrosis. Pink eye (conjunctivitis) generally remains contagious as long as your child has tearing and matted eyes. As stated in the methods section, hands and feet were the first regions to show blue-coloured sweat. All swabs and skin scrapings were negative for fungi. Case reports of infectious pseudochromhidrosis and causative microorganisms. Chromhidrosis is a rare chronic condition that causes sweat to turn black, blue, green, yellow, or brown. Read the reviews and add your own to help us continue to earn this wonderful recognition each year. Chromhidrosis is a rare, chronic condition characterized by color in your sweat. It's. Erlangen: Caister Academic Press, 2008. One area of the body that commonly becomes sweaty is the feet. Rifampin and red urine. The color may only affect sweat in certain areas or sweat all over the body. Eccrine chromhidrosis. If we combine this information with your protected Whether promethazine is the sole trigger is currently unknown. health information, we will treat all of that information as protected health Mayo Clinic. The infectiousness of this disorder has been exemplified in other studies (36, 44) as well as by the current case report. Bacillus cereus, a volatile human pathogen. Yellow pseudochromhidrosis in a young female. Hyperhidrosis - Symptoms and causes - Mayo Clinic Chromhidrosis has several subtypes, which are described separately on DermNet. Combined use of ranitidine (H2-recepter antagonist) and lansoprazole (proton pump inhibitor) may trigger Bacillus colonization, as reported by Hill et al. Certain activities such as hot showers and friction against the skin increase the likelihood of discolored sweat in people with chromhidrosis. Bronchitis: Causes, Symptoms, Diagnosis & Treatment - Cleveland Clinic Yamada-Ankei T, Iwasaki H, Mori T. Production of copper coproporphyrin III by Bacillus cereus. Shulka et al. Other possible reasons for the appearance of colored sweat include infection, blood in the sweat (hematohidrosis), excess bilirubin (an orange-yellow pigment formed in the liver), and/or poisoning. Infectious Pseudochromhidrosis: A Case Report and Literature Review